Orphanet J Rare Dis. 2025 Apr 21;20(1):191. doi: 10.1186/s13023-025-03680-w.ABSTRACTBACKGROUND: This study aims to investigate the clinical characteristics, imaging features, treatment, and prognostic factors of jaw Langerhans cell histiocytosis (JLCH), providing valuable insights for its clinical d
Br J Cancer. 2025 Apr 19. doi: 10.1038/s41416-025-02993-8. Online ahead of print.ABSTRACTBACKGROUND: Metastatic, castration-resistant prostate cancer (mCRPC) directly contributes to the mortality and morbidity of prostate cancer. It is imperative to identify new molecular targets and discover effect
Sci Rep. 2025 Apr 18;15(1):13429. doi: 10.1038/s41598-025-97885-5.ABSTRACTSelf-reported pain scores are often used for pain assessments and require effective communication. On the other hand, observer-based assessments are resource-intensive and require training. We developed an automated system to
JBJS Case Connect. 2025 Apr 17;15(2). doi: 10.2106/JBJS.CC.24.00487. eCollection 2025 Apr 1.ABSTRACTCASE: A 53-year-old, right-hand-dominant gentleman suffered a traumatic right scapulothoracic dissociation with severe soft tissue damage and complete right arm paralysis following a high-speed all-te
Insights Imaging. 2025 Apr 17;16(1):88. doi: 10.1186/s13244-025-01962-2.ABSTRACTArtificial intelligence (AI) is transforming radiology by improving diagnostic accuracy, streamlining workflows, and enhancing operational efficiency. However, these advancements come with significant sustainability chal
Adv Healthc Mater. 2025 Apr 17:e2402882. doi: 10.1002/adhm.202402882. Online ahead of print.ABSTRACTReplicative senescence presents a significant challenge in mesenchymal stem cell (MSC) expansion due to high reactive oxygen species (ROS) levels generated during culture. Elevated ROS levels lead to
Mater Today Bio. 2025 Mar 28;32:101715. doi: 10.1016/j.mtbio.2025.101715. eCollection 2025 Jun.ABSTRACTWound healing presents a significant challenge in healthcare, imposing substantial physiological and economic burdens. While traditional treatments and stem cell therapies have shown benefits, milk
Cancers (Basel). 2025 Mar 31;17(7):1183. doi: 10.3390/cancers17071183.ABSTRACTGlobally, breast cancer is both the most common cancer and the most common cause of death related to cancer among women. It is estimated that over 2 million women were diagnosed with breast cancer in 2022 worldwide, while
Antioxidants (Basel). 2025 Feb 24;14(3):258. doi: 10.3390/antiox14030258.ABSTRACTOxidative stress, which is characterized by an imbalance between reactive oxygen species (ROS) production and antioxidant defenses, has critical roles in the initiation, progression, and treatment of gastric cancer. On
BMC Surg. 2025 Apr 11;25(1):153. doi: 10.1186/s12893-025-02870-4.ABSTRACTBACKGROUND: It is of the utmost importance in the prevention of infections in surgery that nursing students should learn surgical aseptic skills fully and in the correct order. There is a need for innovative teaching strategies
Bull Cancer. 2025 Apr 10:S0007-4551(25)00082-7. doi: 10.1016/j.bulcan.2024.03.010. Online ahead of print.ABSTRACTOsteosarcoma (OS) and Ewing Sarcoma (ES) are the two most frequent malignant bone tumors in children, adolescents and young adults. In case of disease recurrence, both are characterized b
No abstractHand Clin. 2025 May;41(2):xiii-xiv. doi: 10.1016/j.hcl.2025.02.001. Epub 2025 Mar 3.NO ABSTRACTPMID:40216518 | DOI:10.1016/j.hcl.2025.02.001
Hand Clin. 2025 May;41(2):223-230. doi: 10.1016/j.hcl.2024.12.011. Epub 2025 Feb 7.ABSTRACTThe conventional approach to surgical training has long followed a master-apprentice model, where experienced surgeons teach trainees in a patient-involved setting. This method has effectively educated surgeon
J Biol Chem. 2025 Apr 8:108489. doi: 10.1016/j.jbc.2025.108489. Online ahead of print.ABSTRACTThe crosstalk between microglia and astrocytes following spinal cord injury (SCI) greatly decides the prognosis. However, a comprehensive understanding of the molecular mechanisms by which microglia regulat
Breast Cancer. 2025 Apr 10. doi: 10.1007/s12282-025-01699-2. Online ahead of print.ABSTRACTBACKGROUND: Upper extremity impairments in patients with breast cancer persist after curative surgery. Although postoperative factors associated with upper extremity impairments have been reported, modifiable
Curr Opin Otolaryngol Head Neck Surg. 2025 Apr 3. doi: 10.1097/MOO.0000000000001045. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: Trismus (decreased mouth opening) is frequently associated with oral premalignant/malignant lesions, and also occurs in upto 40% of head neck cancer patients post rad
Funct Integr Genomics. 2025 Apr 9;25(1):84. doi: 10.1007/s10142-025-01587-0.ABSTRACTObesity, characterized by the excessive accumulation of white adipose tissue, is a significant global health burden and a major risk factor for a range of diseases, including malignancies and metabolic disorders. Ind
Cell. 2025 Apr 4:S0092-8674(25)00286-7. doi: 10.1016/j.cell.2025.03.013. Online ahead of print.ABSTRACTThe plasma proteome is maintained by the influx and efflux of proteins from surrounding organs and cells. To quantify the extent to which different organs and cells impact the plasma proteome in he
BMC Musculoskelet Disord. 2025 Apr 8;26(1):346. doi: 10.1186/s12891-025-08612-0.ABSTRACTBACKGROUND: Carpal tunnel syndrome (CTS) is the most common peripheral nerve compression neuropathy. While established surgical techniques have demonstrated reliable outcomes and safety profiles, innovations in m
Biosens Bioelectron. 2025 Apr 3;280:117442. doi: 10.1016/j.bios.2025.117442. Online ahead of print.ABSTRACTThe diagnostic options for monitoring fracture healing are currently limited to methods that expose patients to ionizing radiation, i.e. X-rays or computed tomography. The development of new me
Plast Reconstr Surg Glob Open. 2025 Apr 4;13(4):e6680. doi: 10.1097/GOX.0000000000006680. eCollection 2025 Apr.ABSTRACTFractures at the base of the proximal phalanx of the thumb pose significant challenges including joint stability, precise reduction, and functional recovery. These injuries can lead
NPJ Digit Med. 2025 Apr 7;8(1):190. doi: 10.1038/s41746-025-01587-1.ABSTRACTSepsis real-time prediction models (SRPMs) provide timely alerts and may improve patient outcomes but face limited clinical adoption due to inconsistent validation methods and potential biases. Comprehensive evaluation, incl
Int J Biol Macromol. 2025 Apr 2;309(Pt 1):142816. doi: 10.1016/j.ijbiomac.2025.142816. Online ahead of print.ABSTRACTSkin wound repair, a highly integrated and overlapping process, is susceptible to infection, hyperoxia and excessive inflammation, which can delay wound healing or even lead to chroni
J Hand Surg Glob Online. 2025 Jan 9;7(2):181-185. doi: 10.1016/j.jhsg.2024.11.013. eCollection 2025 Mar.ABSTRACTPURPOSE: The advent of large language models (LLMs) like ChatGPT has introduced notable advancements in various surgical disciplines. These developments have led to an increased interest i
